عکس بازیگران عکس بازیگران

Causes of lymphocytosis in Abidjan: a preliminary study



AIM We set out to identify the causes of  lymphocytosis in adults in Abidjan by the use  of cytology combined with flow cytometry.

METHODS We recruited 39 patients with  either an organomegaly or a persistent lymphocytosis  above 4 x 109 lymphocytes/L lasting more than 3 months or both presentations. We performed full blood count and immunophenotyping by flow cytometry. We also calculated the Matutes score with the following markers: CD5, CD23, CD22 or CD79b, FMC7 and the surface immunoglobulin (sIg).

RESULTS The mean age of the study patients was 60.28±9.93 with a mean absolute lymphocyte count of 64.5±69.5 109/l. The commonest cause of lymphocytosis in our study was circulating  phases of non-Hodgkin lymphoma followed by chronic lymphocytic leukaemia.

CONCLUSION Patients presenting with lymphocytosis in Abidjan are likely to have chronic B-cell lymphoproliferative disorder.  This finding will inform guidelines for diagnosis and management of chronic lymphoproliferative disorders in Sub-Saharan Africa.


Lymphocytosis; Lymphoma; Immunophenotyping; Cote d'Ivoire; Africa.

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