Table 2: Factors Related To Platelet Nadir Counts
|
Parameters |
Category |
Cycle 1 |
Cycle 2 |
||
|
Median(Range) x109/L |
P Value |
Median(Range) x109/L |
P Value |
||
|
Age Groups in Years |
>=60 |
147.5(130-205) |
p=0.025 |
79.6(20-200) |
p=009 |
|
<60 |
169.5(104-453) |
117(28-360) |
|||
|
Baseline TLC ( x109/L) |
<1.3 |
152(130-255) |
p=0.020 |
117(20-346) |
p=0.502 |
|
1.3-1.9 |
170(135-359) |
106(32-357) |
|||
|
2-2.9 |
166(104-421) |
113(28-360) |
|||
|
3-3.5 |
319(163-453) |
128(59-169) |
|||
|
>3.5 |
192(169-215) |
95.4(82-109) |
|||
|
Baseline PLT count (x109/L) |
100-149 |
138.5(130-170) |
p=0.021 |
77(61-154) |
p=0.029 |
|
150-249 |
158.5(133-229) |
90.6(56-177) |
|||
|
250-349 |
161.5(112-359) |
127(32-346) |
|||
|
350-449 |
176(104-421) |
101.5(20-357) |
|||
|
>449 |
179(146-453) |
119.37(56-360) |
|||
TLC,
total lymphocyte count; PLT, platelet. Median
nadir platelet counts were used for comparisons because platelet nadir
counts
in both cycles had a non-normal distribution. This table shows that low
nadir counts
were associated with (a) old age (≥60) in both cycles, (b) low
baseline total
lymphocyte count in cycle 1, and (c) low baseline platelet counts in
both
cycles.